Metagenomics analyzes make possible to determine the diversity and amounts of microorganisms in a sample. Identification of bacteria with the 16S rRNA gene with a length of ~ 1500 bp is now a standardized process. However, most of the new generation sequencing methods used only a portion of this gene which is approximately ~ 450 bp in length and therefore produce erroneous results. Oxford Nanopore enhanced the resolution of species identification by reading the entire 1500 bp 16S rRNA gene thanks to its long reading technology and opened a new page in this field. Metagenomic analyzes provide a large number of possibilities for detailed examination of a wide variety of sample types, or components of a sample.

Discover with our Amplicon Sequencing Service – a targeted genetic analysis solution designed to unlock precise insights from DNA or RNA samples. By selectively amplifying and sequencing specific regions of interest, we provide you with focused, high-resolution data, perfect for pinpointing mutations, unraveling genetic diversity, and tracking variations. Our cutting-edge technology ensures accurate results even from limited genetic material, empowering you to make informed decisions swiftly and cost-effectively. From medical breakthroughs to environmental exploration, our Amplicon Sequencing Service is your pathway to streamlined, impactful genetic analysis.

Our Services Laboratory offers RNA-Seq services for a wide range of analyses, including differential gene expression (DEGs), fusion gene discovery, and variant identification, including single nucleotide variations (SNVs) and insertions/deletions (Indels). These assessments are carried out by our skilled bioinformaticians using cutting-edge technology and best-in-class algorithms. Our bioinformatics solution enables a high-level overview and detailed data exploration by showing important expression patterns in your RNA data, complemented by heatmap and PCA (Principal Component Analysis) analysis. Enrichment analysis using databases like KEGG, GO, DO, Reactome, and WikiPathways also provide useful insights into the functional implications of your RNA data.

With our customized pipeline for detection of SARS-CoV-2 based on Oxford Nanopore sequencing technology which utilizes the benefits of long reads. Our service aligns the reads to SARS-CoV-2 reference genome, calls variants, and generates a consensus genome sequence. It then determines lineage, clade and phylogenetic tree information of the sample using Pangolin and NextClade. All the information with its data and QC metric files gets summarized in one extensive html report for easy viewing.

Oxford Nanopore Technologies offers a workflow that enables Influenza A and B whole genomes to be amplified by PCR and run 96 different samples in a single flow cell using ligation sequencing chemistry.

Sequencing data of influenza samples are used with our automated analysis program to determine which subtype the Influenza genome belongs to via the Nextclade database (clades.nextstrain.org). The studied data are evaluated and reported with the vaccine strains of Influenza A and B virus types in this database.